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Diagnostic Pitfalls

It cannot be emphasized enough that diagnosis and assessment for operability must be carried out by experienced healthcare professionals at expert centers.1


Current Shortcomings

  • Screening for CTEPH is not common practice. In a pulmonary hypertension (PH) registry, 43% of patients with pulmonary arterial hypertension (PAH) were diagnosed without a ventilation/perfusion (V/Q) scan.2

  • Screening PH with computer tomography pulmonary angiography (CTPA) often doesn’t recognize CTEPH.3

  • Patients with CTEPH can present without a history of deep vein thrombosis (DVT) or pulmonary embolism (PE).4

  • Failure to refer to an expert PH center may result in a patient being wrongly assessed as inoperable.1


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Useful resources

Our resources page contains a range of material to help with the identification, diagnosis and management of CTEPH.

A list of expert centers can be found here.


1. Jenkins D et al. Eur Respir Rev 2012;21:32–9. 2.McLaughlin VV et al. Chest 2013;143:324–32. 3.Galiè N et al. Eur Respir J 2015; 46: 903–75. 4.Pepke-Zaba J et al. Circulation 2011;124:1973–81.